ESPN GameDay picks for Clemson-Louisville

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The ACC game between No. 2 Clemson and Louisville at Memorial Stadium will start at noon on Saturday.

The Tigers (7-0) are currently a 39-point favorite against the Cardinals (2-6) and ESPN's Football Power Index has Clemson as a 99.2% home favorite.

ESPN’s College GameDay panel weighed in with their predictions live:

Desmond Howard picked Clemson:

Celebrity guest picker picked Clemson:

Kirk Herbstreit picked Clemson:

Lee Corso picked Clemson:

David Pollack picked Clemson:

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