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If Bird Flu hits, we're better prepared than when COVID hit...
General Boards - COVID
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If Bird Flu hits, we're better prepared than when COVID hit...


Apr 27, 2024, 2:47 PM
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https://wapo.st/3xWtfxt

Leana Wen is a doctor & health expert. I think what she's saying makes sense. We shouldn't panic if bird flu hits, for a few reasons:

1) Personal Protective Equipment is more accessible - Masks, goggles, and gowns won't be as difficult to procure, unlike in early 2020. So, the population and healthcare providers shouldn't struggle to ramp up if needed for things like masks.

2) Tamiflu - This can treat bird flu if given early enough, and it can be given to people who aren't yet infected to prevent them getting ill. Millions of doses might be needed. But it's something that's expected to work against bird flu.

3) Vaccines - There are vaccines using multiple technologies could be ramped up quickly within months. This isn't like Covid, where we had to wait almost a year for vaccine development & testing. Vaccines for the bird flu already exist, and millions could be released within weeks.

We should be concerned about H5N1. But it's very likely that we'll be better prepared than we were in 2020.

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Here's how H5N1 was found in cows. Interesting video. You'd think the CDC or

1

Apr 30, 2024, 12:29 PM
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USDA found the virus. Nope. Basically a vet was treating a bunch of sick cows. The farmer mentioned half his cats had also recently died. Cats were positive for H5N1. Then they tested milk and it was positive. Luckily, the cows don't seem to be dying much from it. But the cats are. Farm workers have also been seen having flu-like symptoms as well. Now this could have come from a cat who ate a bird who gave it to cows and the farmers. We keep concentrating on the cows, but the cats may be the originators on these farms.

https://www.youtube.com/watch?v=N81wf0we3p0

And if you want to know how screwed up this is, farmers are refusing to let their cattle be tested for fear of having their herds slaughtered or being sold. You now have to ask yourself, just as I did countless times with covid, what is the science NOT BEING DONE that would provide answers? Here's what the CDC should do, assuming they're still "public health" and not top-secret need-to-know health.

They should do a proper, randomized, seroprevalence testing study among US cattle workers, particularly those on farms with cow herds known to have been infected. When people are exposed to influenza, they create antibodies, whether they ever feel sick or not. It is essential to know how many, if any, others have been exposed without illness. If 97% of farm workers carry antibodies, like with influenza-d for example, without illness, then this is a virus we don't need to worry about. If only 1-3% or workers are positive for antibodies, this is still a serious virus we need to watch.

Seroprevalence studies (as usual) have been done and published in other countries, but only with poultry workers. I saw at least 4-5 studies and all had numbers less than 5% (not good). But with cows and cats now infected on farms, this needs to be done on cattle farms here in the US. But I haven't heard a peep about this even being considered, much less done, and that's why this is so similar to covid. Hush hush. And the reason for that is simple. Wait it out as long as possible until it pops in another country then you can call it the Indian flu, or the Singapore flu, or the Brazil flu. No one wants to be the first outbreak, and it will be hidden until it can't be hidden anymore.

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CDC found H5N1 in 100% of commercial pasteurized milk sampled in SC.


May 25, 2024, 11:29 AM
Reply

Never fear though. They only tested 3 samples. 3 of 3 were positive for bird flu. None grew in eggs though so they've concluded the virus isn't viable after pasteurization.


https://www.fda.gov/food/alerts-advisories-safety-information/updates-highly-pathogenic-avian-influenza-hpai

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Re: If Bird Flu hits, we're better prepared than when COVID hit...


Jun 13, 2024, 8:00 PM
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I service chicken houses. I have been hearing about the horrendous coming "bird flu" for a long time. Still not being transmitted to humans at any significant rate.

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Re: If Bird Flu hits, we're better prepared than when COVID hit...


Jun 14, 2024, 1:44 PM
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Agree there is no need to panic, but despite Tamiflu, vaccines, PPE, etc. if this is so virulent that in past outbreaks it had a 50% mortality rate, that is a concern.

I believe I read of a Mexican citizen who recently died from this, but this person had significant comorbidities.

I wonder how many people were infected in the past and what were their comorbid conditions.

Hopefully we have learned a few things and the days of spacing 6 ft apart, closing beaches and boat landings, plexiglass barriers, etc are a thing of the past.

Good article and thanks for posting.

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Bird flu outbreak in Colorado.


Jul 17, 2024, 1:13 AM
Reply

Poultry egg laying farm 150 workers were culling chickens who had bird flu. 69 workers have come down with flu symptoms. 5 have tested positive for bird flu. Genetic analysis shows the chicken fark workers, and chickens, have the bovine/cow strain. Meaning the bird flu can go from cows to chickens to humans fairly easy. Still no human to human transmission but working around cows and chickens is more dangerous.

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The story of human existence is a constant battle with disease, dying from it,

1

Jul 17, 2024, 8:29 AM
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adapting to it, and eventually surviving it.

Thankfully, we are much better prepared today than at any other time of human existence to combat disease and significantly shorten the dying phase. Overall, I'm pretty comfortable with the idea that disease (especially viral infections) are a fact of of our existence and something we will always have to deal with.

Panic rarely solves anything and in too many cases panic interferes with finding real solutions. I feel that much of our Government's reaction to COVID (local, State, and Federal) was so panic and politically driven that it yielded a lot of stupid and draconian nonsensical responses.

If the bird flu becomes the next big disease for humans, I certainly hope we don't lose our ever loving minds over it and avoid politicizing the outbreak like we did with COVID.

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I may have missed it

1

Jul 17, 2024, 9:03 AM
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but I haven't read a detailed account of what was done right, what was done wrong and what should have been done regarding COVID.

Without an honest assessment of the response to COVID which would hopefully restore some degree of confidence in the CDC, NIH, etc., I suspect we'll flail away with the next big thing too.

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You are correct - there has not been a soup to nuts accounting of the USA's

1

Jul 17, 2024, 11:06 AM
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response to COVID.

We are in desperate need of a full accounting by folks who were not involved in the COVID policy formulation that may have a scalp to loose for their actions. That means no Fauci or any of the folks in the NIH, CDC, WHO, or any other policy making positions during COVID.

We need the band-aid to be ripped off all our COVID actions/policies that lets the chips fall where they may. Of course we'll never get that kind of truth finding because inevitably - quite a lot of bureaucrats and politicians would be found to have been full of shid making policy decisions based on total BS, political considerations, or personal desires/opinions.

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Ok, I finally found a resource with complete data on H5N1......


Aug 6, 2024, 10:25 AM
Reply

Attached is a list of bird species who have tested positive just in SC. Also attached is a full list of mammal species nationwide who have tested positive.

I'm telling you, we have some immunity to H5N1. For pigs and humans to still be relatively safe, after this much exposure, I'm thinking we already have some immunity to this from an older swine flu variant.

Keep in mind, most human immunity to avian influenza comes from pigs, not birds. Pigs have both avian and human influenza receptors, and what usually happens is pigs, with close contact, become the mixing bowl where mutations happen that lead to a jump to humans. Pigs are the intermediary, often. Avian flu does not transmit to humans easily (takes direct contact and a large exposure). It's rare. But a pig can easily get it, and in the pig population it can mutate (easier) to infect humans, and this is why pigs, among some other animals (ferrets, etc), are the ones to watch.

The Spanish flu in 1918 was a variant of H1N1. It was a swine flu, boosted and made novel by avian genes. 2009, was H1N1, swine flu, boosted by novel avian genes. They did studies after the 2009 "swine" flu and learned it provides immunity to a slew of avian flu viruses. I'm thinking the H5N1 circulating today is one of those avian flu variants that 2009 antibodies have some success with.

Anyway, the longer this goes, the more I think we have some immunity. It still bears watching as anything can happen, but as it stands, we're a tough cookie for this virus to infect, along with our tasty pigs.

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They just found pigs infected with H5N1.


Oct 31, 2024, 4:31 AM
Reply

Always said watch the pigs. Pigs carry two varieties of flu receptors in their respiratory tract. One set of cells are unique to pigs. The other is very close to human receptors.

https://www.latimes.com/environment/story/2024-10-30/officials-say-h5n1-bird-flu-has-infected-a-pig-in-oregon#:~:text=In%20'concerning%20development%2C'%20officials,was%20found%20in%20a%20pig.&text=Swine%20are%20considered%20by%20health%20officials%20to%20be%20efficient%20influenza%20mixing%20bowls

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Re: They just found pigs infected with H5N1. (update)


Oct 31, 2024, 9:34 AM
Reply

Side note.....

In Washington state they have several human cases confirmed of H5N1. The human cases in Washington came from birds, not cows. The pig(s)? Also came from birds, not cows. They've confirmed one pig, waiting on others. State labs have confirmed the other pigs, but until the CDC does, it's not "official". Lol.

Most interesting thing is the genomes have not been released by the CDC. Some of the leading influenza scientists on Earth, who SHOULD have the quickest access to this, in the UK for example, have seen nothing released, as far as genomes. These are scientists who know exactly what mutations to look for in what areas, to determine any danger to humans, or not. They're waiting a month or more to see genomes from the CDC.

And like I said, no one wants to be the first here.

Nothing has changed for a very long time.

https://www.paho.org/en/who-we-are/history-paho/purple-death-great-flu-1918

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Well, the latest data shows


Nov 10, 2024, 11:59 AM
Reply

Over 400 infected cattle/dairy farms, 46 human cases confirmed, 7% of cattle workers carry antibodies, and there's a teenager in British Columbia hospitalized with it (and a Missouri case), both with no known exposure. And it's been found in ONE pig.

It's working hard on us, but so far we're in decent shape. Some additional research shows past flu viruses will provide some immunity to H5N1, which explains why it's wrecked so many bird and mammal species, while humans, and pigs, have been relatively unaffected. BUT, this study was done with the cow variant, not the bird/poultry version.

The problem is the animal world now carries this flu, and there are several variants. The cow version is relatively mild for humans, but it kills over 50% of cats. It's the bird version (some of those 46 human infections are from birds) is a different variant of H5N1 and that is more severe. 11 of the 46 infections are in Washington State, from a poultry farm, and that is a different variant of H5N1 than the cows and cattle-workers.

What will likely happen, my guess, is we get an outbreak similar to 2009, a pandemic strain, but only for certain people. IF you got the 2009 pseudo-pandemic H1N1 strain, and had a severe case and were immunologically naïve, OR if you're over 60yo, you're probably saf(er) from a severe case. This will hit younger people, and those who didn't get (very) sick in 2009, the hardest. As did the Spanish Flu. But we will see. What appears likely now, is humans will get some form of this flu in the next year or two.

CDC still has not released full genomes. We are patiently waiting and hoping this blows up somewhere else first. They also released some random PSA few days ago outlining the symptoms of H5N1. Conjunctivitis is one, also seen with covid, because a poorly adapted virus may infect the eyes before the lungs,although it can infect both as well. Below is a pic of a cattle worker from Texas infected with H5N1, a "mild" case of conjunctivitis (they lied). Don't think pink eye. Think bleeding eyes. He also had respiratory symptoms.



Oh, and to show this isn't a fake picture (from the CDC)....
https://www.nejm.org/doi/10.1056/NEJMc2405371?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Teenager in British Columbia:
https://news.gov.bc.ca/releases/2024HLTH0152-001583

Missouri case:
https://www.cdc.gov/bird-flu/spotlights/missouri-h5n1-serology-testing.html

Forgot to mention, H5N1 has popped up unexpectedly in a Los Angeles sewershed.
https://lacounty.gov/2024/11/01/h5-avian-flu-detected-at-wastewater-sampling-site-in-los-angeles-county-public-health-closely-monitoring-situation/

Study on H1N1/H1N5 immunity (was with ferrets) but they are good proxies to study influenza.
https://www.biorxiv.org/content/10.1101/2024.10.23.619881v1

Got the 7% seropositivity study among cattle workers from here:
https://www.science.org/content/article/many-human-infections-cow-flu-are-going-undetected

The one pig identified:
https://www.aphis.usda.gov/news/agency-announcements/federal-state-veterinary-agencies-share-update-hpai-detections-oregon


Message was edited by: Tiggity® to give reputable primary sources so people don't think I'm making stuff up or passing along "misinformation".

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