Replies: 23
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Oculus Spirit [97386]
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Some new numbers. If you got the Moderna vaccine
Sep 11, 2021, 2:54 AM
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You're 92% protected from showing up at an emergency room or urgent care with covid. And 95% protected from being hospitalized. This is higher than Pfizer and far higher than J&J
https://t.co/lsuqXTtZdl?amp=1
Just for those maybe 7 people still trying to decide on a vaccine.
Moderna also has over 3 times the mRNA per shot dose over Pfizer. Also produces 2.5 times the antibodies. Downside you will probably feel crappier for a day or two compared to Pfizer.
Get the vaccine on a Friday and you should feel fine by Monday.
The data above applies to Delta too. Only mildly tainted by pre delta data. Data is June through August... And vast majirity cases during the period (mostly in August) are delta.
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CU Medallion [59722]
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Now do me!!
Sep 11, 2021, 3:05 AM
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I had COVID and the Moderna shot. Are you telling me that I am invincible?
Well….other than all the other things that have cropped up since getting the shot. I wish I would have stuck with natural immunity. I have never in my life had so many health issues.
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All-In [34357]
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But yer "92% protected" , whatever the **** that means...***
Sep 11, 2021, 5:36 AM
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Lot o points [162143]
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^^^ failed statistics classes ^^^***
Sep 11, 2021, 7:12 AM
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All-TigerNet [12399]
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Re: Some new numbers. If you got the Moderna vaccine
Sep 11, 2021, 9:31 AM
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You're 92% protected from showing up at an emergency room or urgent care with covid. And 95% protected from being hospitalized. This is higher than Pfizer and far higher than J&J https://t.co/lsuqXTtZdl?amp=1Just for those maybe 7 people still trying to decide on a vaccine. Moderna also has over 3 times the mRNA per shot dose over Pfizer. Also produces 2.5 times the antibodies. Downside you will probably feel crappier for a day or two compared to Pfizer. Get the vaccine on a Friday and you should feel fine by Monday. The data above applies to Delta too. Only mildly tainted by pre delta data. Data is June through August... And vast majirity cases during the period (mostly in August) are delta.
I've been reading the same and am glad to hear this. My wife got Moderna early in the year and I got Pfizer. I heard it for weeks from her that she got the Yugo version of the vaccine while I got the BMW 7 series version. She's in health care also and was convinced Pfizer was a better product.
I told her she was driving in style now as the studies look better for Moderna.
Is there any info out that would advise against taking Moderna as the 3rd shot over Pfizer if one originally took Pfizer? I realize Moderna is not on the fast track for 3rd shot approval and is discussing cutting the dose in half and also even looking to market a combo COVID/Flu shot(pass on that).
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Legend [17040]
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Moderna vaccine has worked great for me.
Sep 11, 2021, 9:53 AM
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When 7 year old grandson had mild case of COVID this summer, wife and I had nothing even given he was staying at our house every weekday.
Good stuff …
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All-In [40798]
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I got covid three months after my second moderna shot
Sep 12, 2021, 5:48 PM
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my wife had pfizer and didn't catch it from me with zero social distancing and me sneezing and coughing the first few days thinking it was allergies until it got worse
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Team Captain [487]
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Re: Some new numbers. If you got the Moderna vaccine
Sep 11, 2021, 10:33 AM
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Man, you’re hard to take from the perspective of someone that doesn’t trust modern medicine. My Dad resigned his commission as a Lt Col & then spent another 20 yrs in private practice. The vaccines are the definition of a cluster f u c k.
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Team Captain [487]
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Re: Some new numbers. If you got the Moderna vaccine
Sep 11, 2021, 10:48 AM
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Our wonderful gubmint participated in the creation of this virus & vaccine. Simply put it’s a huge money making scam that enriches lobbyists , lawmakers & big pharma. Also kills poor mf’rs with comorbidities & theres a lot of those poor ########, win , win. We need to depopulate , right! Otherwise therapeutics would be encouraged but they’re not because therapeutics are cheap. No money in therapeutics, no point in that.
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Oculus Spirit [97386]
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Re: Some new numbers. If you got the Moderna vaccine
Sep 11, 2021, 11:38 AM
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This all sounds totally reasonable.
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Team Captain [487]
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Re: Some new numbers. If you got the Moderna vaccine
Sep 11, 2021, 11:42 AM
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Yep, nobody would believe it,safe.
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CU Medallion [57939]
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Okay - straight to the point - simple question:
Sep 11, 2021, 11:42 AM
[ in reply to Re: Some new numbers. If you got the Moderna vaccine ] |
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Are you suggesting that people should not get the vaccines, and instead take their chances with covid?
Yes or no. Let's see if you can give a direct answer.
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Team Captain [487]
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Re: Okay - straight to the point - simple question:
Sep 11, 2021, 12:15 PM
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I believe your chances are just as good with therapeutics & natural immunity. The flu didn’t go away.
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Team Captain [487]
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Re: Okay - straight to the point - simple question:
Sep 11, 2021, 12:17 PM
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Vaccines are a choice , do what makes you feel safe. Wish you all the best. I don’t want to here anything from the vaccine mandate tyrants, they’re either clueless or have an agenda.
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Team Captain [487]
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Re: Okay - straight to the point - simple question:
Sep 11, 2021, 12:18 PM
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Hear.
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Team Captain [487]
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Re: Okay - straight to the point - simple question:
Sep 11, 2021, 12:32 PM
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Do I really have to point out that 99 & whatever % of people survive covid without repercussions.
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Team Captain [487]
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Re: Okay - straight to the point - simple question:
Sep 11, 2021, 12:36 PM
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& based on what Ive read infections are up compared to a yr ago when we had no info about vaccine efficiency.
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CU Medallion [57939]
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Wow.
Sep 11, 2021, 12:55 PM
[ in reply to Re: Okay - straight to the point - simple question: ] |
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I know at least 50 people who have died from covid. I don't know anybody who has died, or even had an adverse reaction from the vaccine. I know about 20 fully vaccinated people who have gotten covid, including my wife and daughter (and now maybe me); none had anything more than cold/mild flu symptoms. On the other hand, I know about 10 unvaccinated people who got covid; 7 were hospitalized, 6 were put on ventilators, 2 died. So, according to all stats, and more importantly, in my personal experience, the vaccines are highly effective at preventing death and hospitilization. So people can take all of their crazy ###, lying conspiracy bullshat and stuff it.
There is no natural immunity to covid, per se, at least for a lot of people. That's why millions have died from covid, so "natural immunity" when there is a proven, effective vaccine, is an idiotic strategy, endorsed only by idiots and morons. At this point, there are no effective theraputics on the market that doctors are widely prescribing, so that's out the window as well. When they become available, and when MY doctors tell me that's the way to go, I'm all in. I'm not taking medical advice from random people on the internet.
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Team Captain [487]
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Re: Wow.
Sep 11, 2021, 1:35 PM
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Well , I don’t understand why you would get in the mud & start name calling . I guess that’s on you, you do you. My experience with wuflu has been a 180 from yours , sorry for your loss . Do I have to mention that I doubt your sincerity.
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Team Captain [487]
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Re: Wow.
Sep 11, 2021, 1:49 PM
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?
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Orange Blooded [4945]
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Re: Wow.
Sep 12, 2021, 5:13 PM
[ in reply to Wow. ] |
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Get out in direct sunlight for at least 20 minutes per day and take 4,000 units of Vitamin D, K2.
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Orange Blooded [4679]
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Re: Wow.
Sep 12, 2021, 5:20 PM
[ in reply to Wow. ] |
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Smiling Tiger you said there is no natural immunity to covid. Can you describe your understanding of natural immunity? I think you have a misunderstanding of the term. I’m not being a jerk , just trying to understand your definition based on your comments.
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Oculus Spirit [97386]
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I'll screw up this thread some more. What IF......vaccines
Sep 12, 2021, 6:15 PM
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were ALSO natural immunity? Because the mRNA vaccines are. 100% Wuhan covid mRNA, same kind the virus uses to replicate in you. So you make antibodies to a 100% authentic PART of the Wuhan virus. It's the same natural process as if you were infected. HOWEVER, you're not exposed to the entire virus as the rest of the virus can kill you. Viral vector vaccines technically are not 100% natural, as they use other viruses, or hosts, to create antibodies, so it's not the same as you would create naturally.
ANYWAY, immunity is the ability for you to possess antibodies to rid the virus, when infected. That can be the result of a natural infection, or a vaccine. Strong immunity, you never know you had it. Weak, you get sick. None, you get VERY sick.
And what will really blow people's minds, is immunity doesn't matter with covid, other than keeping you from dying. Immunity is only the extent to which you can produce antibodies to kill the virus, ONCE your immune system knows you're infected. The virus' best trick is to shut down your immunity for DAYS before you can use your immunity....."natural" or vaccine. Doesn't matter. You get it, it replicates, and you spread it. Only after the virus has really done what it needs to do, does immunity even come into play, as you try and rid the virus. That's why vaccinated people, recovered people, and everyone really, does 90% of what the virus needs to do to thrive and evolve, before their first sniffle. Immunity only matters after the fact. Once you know to produce, call up, whatever, antibodies, the virus has already infected you, shut down your interferons that CALL UP antibodies, and spread for several days. You have reached your peak viral load before you know it, before your immune system (equipped with whatever) knows it. As such, your body then finds itself highly infected with a virus, all of a sudden. It then can call up antibodies from a prior infection, vaccine, whatever, and it has a big job killing the virus. If you have no immunity (vaccine or otherwise) your body has to start from scratch creating antibodies, and by then you're behind the 8-ball in the infection, and many people can't recover from it.
The picture below illustrates this using ct values to show viral loads between those unvaccinated and those vaccinated with mRNA vaccines, with delta. Notice the initial viral load is high, and consistent vaccinated or not. After about 6 days, your body then realizes and identifies the infection, and responds. Between day 6 and day 10 you can clear the virus, if "immune". Otherwise, it's a long process that can be deadly. Children possess far more interferons than adults, suppression is less for them, and they can recover easier, and faster. Alpha was more transmissible than Wuhan because it increased interferon suppression. That increases the time infected, and spreading before symptoms appear. That also impacts viral loads. Between Alpha and Delta, the virus evolved this trick further, making Delta suppression interferons more, for longer, and it becomes even more transmissible and with an even higher viral load. This whole process occurs independently from vaccines or immunity.
This is why CT values for covid PCR tests are generally around 32. That catches 90% of covid infections, maybe more. For this study 50 was the cutoff, as you're clinically not contagious or symptomatic at that point. It would be interesting to conduct this same study with those naturally recovered. There may be factors being exposed to the ORF sections of the genome that may produce immunity prior to what is shown in this test. Or it may just be so much better you never get symptoms, or it could cut that initial immune suppression. That is a key thing to study long term. Influenza has been shown to use this same trick, but NOWHERE to the extent covid does. But it uses it to stay in circulation perpetually. This is why covid doesn't end. And most people's idea of "immunity" or even herd immunity, doesn't apply to covid. Immunity heals you and keeps you from dying. It does not stop the virus from spreading.
https://www.medrxiv.org/content/10.1101/2021.07.28.21261295v1.full-textVirological and serological kinetics of SARS-CoV-2 Delta variant vaccine-breakthrough infections: a multi-center cohort study Objectives Highly effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed but variants of concerns (VOCs) with mutations in the spike protein are worrisome, especially B.1.617.2 (Delta) which has rapidly spread across the world. We aim to study if vaccination alters virological and serological kinetics in breakthrough infections.
Methods We conducted a multi-centre retrospective cohort study of patients in Singapore who had received a licensed mRNA vaccine and been admitted to hospital with B.1.617.2 SARS-CoV-2 infection. We compared the clinical features, virological and serological kinetics (anti-nucleocapsid, anti-spike and surrogate virus neutralization titres) between fully vaccinated and unvaccinated individuals.
Results Of 218 individuals with B.1.617.2 infection, 84 had received a mRNA vaccine of which 71 were fully vaccinated, 130 were unvaccinated and 4 received a non-mRNA. Despite significantly older age in the vaccine breakthrough group, the odds of severe COVID-19 requiring oxygen supplementation was significantly lower following vaccination (adjusted odds ratio 0.07 95%CI: 0.015-0.335, p=0.001). PCR cycle threshold (Ct) values were similar between both vaccinated and unvaccinated groups at diagnosis, but viral loads decreased faster in vaccinated individuals. Early, robust boosting of anti-spike protein antibodies was observed in vaccinated patients, however, these titers were significantly lower against B.1.617.2 as compared with the wildtype vaccine strain.
Conclusion The mRNA vaccines are highly effective at preventing symptomatic and severe COVID-19 associated with B.1.617.2 infection. Vaccination is associated with faster decline in viral RNA load and a robust serological response. Vaccination remains a key strategy for control of COVID-19 pandemic.
### Competing Interest Statement
BEY reports personal fees from Roche and Sanofi, outside the submitted work. All other authors declare no competing interests.
### Funding Statement
This study was funded by grants from the Singapore National Medical Research Council (COVID19RF-001, COVID19RF-008). The funders had no role in the design and conduct of the study;url=https://www.medrxiv.org/content/10.1101/0.001). PCR cycle threshold (Ct) values were similar between both vaccinated and unvaccinated groups at diagnosis, but viral loads decreased faster in vaccinated individuals. Early, robust boosting of anti-spike protein antibodies was observed in vaccinated patients, however, these titers were significantly lower against B.1.617.2 as compared with the wildtype vaccine strain.
Conclusion The mRNA vaccines are highly effective at preventing symptomatic and severe COVID-19 associated with B.1.617.2 infection. Vaccination is associated with faster decline in viral RNA load and a robust serological response. Vaccination remains a key strategy for control of COVID-19 pandemic.
### Competing Interest Statement
BEY reports personal fees from Roche and Sanofi, outside the submitted work. All other authors declare no competing interests.
### Funding Statement
This study was funded by grants from the Singapore National Medical Research Council (COVID19RF-001, COVID19RF-008). The funders had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; and decision to submit the manuscript for publication.
### Author Declarations
I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Yes
The details of the IRB/oversight body that provided approval or exemption for the research described are given below:
Written informed consent was obtained from study participants of the multi-centre study approved by National Healthcare Group Domain Specific Review Board (NHG-DSRB) (Study Reference 2012/00917). Informed consent for retrospective data collection at National Centre for Infectious Diseases (NCID) was waived (NHG-DSRB reference number 2020/01122).
All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.
Yes
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
Yes
I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.
Yes
The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.
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Orange Blooded [2910]
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Re: Wow.
Sep 12, 2021, 7:27 PM
[ in reply to Wow. ] |
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Truly awful that you know so many that have passed from covid . I would be interested to know what kind of work you do or where you hang out at . I work with a team of 50 that do not wear mask at work ( never have ) some of us go to plants Dailey with 1000’s working in SC, NC and Ga . I have basically lived a normal life style , work , gym , vacations , parties , lake etc and have not come across one person that has passed from Covid .
2 nurses in the family one in Gville one in Spartanburg and they have seen way less Deaths than you have . 3 people in my office got it and was forced to stay at home for week with cold symptoms. I supposedly had it according to some blood work I had it and did not even know it . It’s crazy how it affects some and doesn’t seem to hardly touch so many . Hopefully someone will figure it out soon .
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